DID YOU KNOW? - RASAGILINE & DULOXETINE

Category: Newsletter

Using rasagiline (a Parkinson’s “rescue” drug) together with DULoxetine (commonly known as Cymbalta) is not recommended. 

Combining these medications can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. 

Severe cases may result in coma and even death. In general, you should wait at least 14 days after stopping rasagiline before you start treatment with DULoxetine. 

Conversely, if you have recently been on DULoxetine and are now starting treatment with rasagiline, you should check with your doctor or pharmacist to see how long you should wait before it is safe for you to use rasagiline, as some medications can take a while to clear from your body. 

It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

 

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Updated: August 16, 2017